Two sample MR report
ZNF880_Alveolar Macrophages against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | -0.0806149 | 0.1482336 | 0.6154465 |
| Weighted median | 6 | -0.0474844 | 0.0151200 | 0.0016865 |
| Inverse variance weighted | 6 | -0.0400811 | 0.0117625 | 0.0006555 |
| Simple mode | 6 | -0.0484457 | 0.0210083 | 0.0692496 |
| Weighted mode | 6 | -0.0484457 | 0.0197659 | 0.0578671 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.498478 | 4 | 0.8269110 |
| Inverse variance weighted | 1.573724 | 5 | 0.9044085 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0284074 | 0.1035596 | 0.7974303 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 6.85e-05 | 0 | TRUE | 0.4341652 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
